{"id":75,"date":"2025-02-26T21:34:18","date_gmt":"2025-02-26T21:34:18","guid":{"rendered":"https:\/\/www.zubasti.com\/isurtec\/?page_id=75"},"modified":"2025-03-21T15:35:41","modified_gmt":"2025-03-21T15:35:41","slug":"research","status":"publish","type":"page","link":"https:\/\/www.zubasti.com\/isurtec\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"75\" class=\"elementor elementor-75\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c5a35ad e-con-full e-flex e-con e-parent\" data-id=\"c5a35ad\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-e3bcda8 e-flex e-con-boxed e-con e-child\" data-id=\"e3bcda8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-760c8fe e-con-full e-flex e-con e-child\" data-id=\"760c8fe\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-6025765 e-con-full e-flex e-con e-child\" data-id=\"6025765\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-31a8942 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"31a8942\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">RESEARCH<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a8bddc8 e-con-full e-flex e-con e-child\" data-id=\"a8bddc8\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-554661a elementor-widget elementor-widget-image\" data-id=\"554661a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"420\" src=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/research-head.png\" class=\"attachment-full size-full wp-image-780\" alt=\"\" srcset=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/research-head.png 600w, https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/research-head-300x210.png 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5fac012 e-flex e-con-boxed elementor-invisible e-con e-parent\" data-id=\"5fac012\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-53b9225 elementor-widget elementor-widget-text-editor\" data-id=\"53b9225\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tOur goal is to provide you with the ideal coating for your application as efficiently as possible, using a streamlined, straightforward process.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ec7f51d e-flex e-con-boxed e-con e-parent\" data-id=\"ec7f51d\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8b9f241 e-con-full e-flex e-con e-child\" data-id=\"8b9f241\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f6f7eae accordion1 in-box elementor-invisible elementor-widget elementor-widget-n-accordion\" data-id=\"f6f7eae\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;all_collapsed&quot;,&quot;_animation&quot;:&quot;fadeInUp&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2580\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2580\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> <div class=\"icon-block\"><img loading=\"lazy\" decoding=\"async\" src=\"..\/wp-content\/uploads\/2025\/03\/icon-government-research.svg\" width=\"80\" height=\"80\" \/><\/div><div class=\"text-block\"><h3>Government Research\u00a0<\/h3> <p>ISurTec is strongly committed to research and development, with an interdisciplinary team of scientists and engineers focused on developing new coated products for the scientific and medical communities. Our research is supported by the National Institutes of Health (NIH) through the Small Business Innovative Research Program (SBIR).\u00a0<\/p><\/div> <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"45\" height=\"45\" viewBox=\"0 0 45 45\" fill=\"none\"><rect x=\"-1\" y=\"-1\" width=\"43\" height=\"43\" rx=\"21.5\" transform=\"matrix(-4.37114e-08 -1 -1 4.37114e-08 43 43)\" stroke=\"#69C4EB\" stroke-width=\"2\"><\/rect><path d=\"M17 23.9997L22.7003 18.2997L28.401 24\" stroke=\"#69C4EB\" stroke-width=\"1.5\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"45\" height=\"45\" viewBox=\"0 0 45 45\" fill=\"none\"><rect x=\"44\" y=\"1\" width=\"43\" height=\"43\" rx=\"21.5\" transform=\"rotate(90 44 1)\" stroke=\"#F08119\" stroke-width=\"2\"><\/rect><path d=\"M17 21.0003L22.7003 26.7003L28.401 21\" stroke=\"#F08119\" stroke-width=\"1.5\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-729cf4a e-con-full e-flex e-con e-child\" data-id=\"729cf4a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-e67ef5a e-con-full e-flex e-con e-child\" data-id=\"e67ef5a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ade16c5 elementor-widget elementor-widget-heading\" data-id=\"ade16c5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Coatings for Ureteral Stents - Advancing Ureteral Stent Technology<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e6a1b82 elementor-widget elementor-widget-text-editor\" data-id=\"e6a1b82\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Did you know that 50% of patients with ureteral stents experience complications such as painful encrustation and infections? Over time, ureteral stents and other devices in the urological tract can become encrusted with calcium and magnesium salts. ISurTec\u2019s innovative anti-encrustation coating has demonstrated the ability to reduce calcium deposition by over 80% after just one month. This significant advancement represents a major improvement in patient well-being. A heartfelt thanks to our dedicated team for its efforts and the NIH SBIR program for funding this groundbreaking research <em>(NIH-R44DK097934)<\/em>.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-de5b0b1 e-con-full e-flex e-con e-child\" data-id=\"de5b0b1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-f534e56 e-con-full e-flex e-con e-child\" data-id=\"f534e56\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7f6835d elementor-widget elementor-widget-image\" data-id=\"7f6835d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"687\" height=\"450\" src=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/6854f16f04c95351f87af0386111c893.jpg\" class=\"attachment-full size-full wp-image-842\" alt=\"\" srcset=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/6854f16f04c95351f87af0386111c893.jpg 687w, https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/6854f16f04c95351f87af0386111c893-300x197.jpg 300w\" sizes=\"auto, (max-width: 687px) 100vw, 687px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-c872c19 e-con-full e-flex e-con e-child\" data-id=\"c872c19\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5f85a2f elementor-widget elementor-widget-image\" data-id=\"5f85a2f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"687\" height=\"450\" src=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/d7e0557571308e6c77a86614dd778f68.jpg\" class=\"attachment-full size-full wp-image-854\" alt=\"\" srcset=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/d7e0557571308e6c77a86614dd778f68.jpg 687w, https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/d7e0557571308e6c77a86614dd778f68-300x197.jpg 300w\" sizes=\"auto, (max-width: 687px) 100vw, 687px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-6d1c6c4 e-con-full e-flex e-con e-child\" data-id=\"6d1c6c4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-89df33c e-con-full e-flex e-con e-child\" data-id=\"89df33c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9348a42 elementor-widget elementor-widget-text-editor\" data-id=\"9348a42\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Uncoated PU Ureteral Stent<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-83826fa e-con-full e-flex e-con e-child\" data-id=\"83826fa\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4ba4b25 elementor-widget elementor-widget-text-editor\" data-id=\"4ba4b25\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>ISurTec-coated PU Ureteral Stent<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4c5f2ae elementor-widget elementor-widget-text-editor\" data-id=\"4c5f2ae\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tUreteral stents and other devices in the urological tract can encrust with Ca2+ and Mg2+ salts over time. ISurTec\u2019s anti-encrustation coating reduces Ca2+ deposition > 80% after 1 month.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4231c46 elementor-widget elementor-widget-heading\" data-id=\"4231c46\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Addressing Shunt Failure in Hydrocephalus Treatment<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-32af8c9 elementor-widget elementor-widget-text-editor\" data-id=\"32af8c9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Over 30% of implantable cerebrospinal fluid (CSF) shunts used to treat hydrocephalus fail within the first year. Shunt failure necessitates surgical reintervention, which, if delayed, can lead to severe consequences, including brain damage or death. Implantable silicone shunts have been used successfully for decades to treat this disorder. While silicone is a well-established and biocompatible material for implantation, the primary, often unaddressed, cause of shunt failure is clogging due to embolism and tissue ingrowth. Through funding provided by the NIH SBIR Program, ISurTec is developing a novel coating designed to reduce shunt failure by minimizing cell and tissue adhesion to the shunt material. By improving the longevity and reliability of CSF shunts, we hope to enhance patient outcomes and reduce the need for repeated surgical interventions (NIH-R44NS119007).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-6f4362b e-con-full e-flex e-con e-child\" data-id=\"6f4362b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-27309d5 e-con-full e-flex e-con e-child\" data-id=\"27309d5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-775f09b elementor-widget elementor-widget-heading\" data-id=\"775f09b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Neural Tissue Engineering Scaffolds<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-122fed8 elementor-widget elementor-widget-text-editor\" data-id=\"122fed8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tOur scaffolds will be produced in a standardized format compatible with common electrophysiology equipment, such as multielectrode arrays. The scaffolds are designed to enable high-throughput electrophysiological assays with high predictive power for multiple neurotransmitter systems, including glutamatergic, cholinergic, dopaminergic, serotonergic, noradrenergic, and GABAergic circuits.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-1b7ecb1 e-con-full e-flex e-con e-child\" data-id=\"1b7ecb1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7f94252 elementor-widget elementor-widget-image\" data-id=\"7f94252\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"540\" height=\"372\" src=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/neutral-tissue-engineering-scaffolds.jpg\" class=\"attachment-full size-full wp-image-893\" alt=\"\" srcset=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/neutral-tissue-engineering-scaffolds.jpg 540w, https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/neutral-tissue-engineering-scaffolds-300x207.jpg 300w\" sizes=\"auto, (max-width: 540px) 100vw, 540px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5fd9a58 elementor-widget elementor-widget-heading\" data-id=\"5fd9a58\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Nanofiber Membrane Inserts for 96-well Plates<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-03ee247 e-con-full e-flex e-con e-child\" data-id=\"03ee247\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-491a9a9 e-con-full e-flex e-con e-child\" data-id=\"491a9a9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e2b7de4 elementor-widget elementor-widget-text-editor\" data-id=\"e2b7de4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tISurTec has developed cell culture inserts with a nanofiber membrane for growing cells in a more in vivo-like environment.  The topography of our electrospun membranes mimics the extracellular matrix that cells excrete around themselves as they mature.  Cells can be seeded in suspension in the insert cup or bioprinted on the insert underside.  The nanofiber membranes are electrospun from either permanent materials, such as PET growth surfaces, or materials that biodegrade over time.  Biodegradable membranes allow cells to be grown on both the apical and basolateral sides of the insert membrane eventually forming a mature barrier membrane as the insert membrane degrades.  Please inquire if you are interested in beta testing ISurTec cell culture inserts!\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2580\" class=\"elementor-element elementor-element-b221eeb e-con-full e-flex e-con e-child\" data-id=\"b221eeb\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4bbafdc elementor-widget elementor-widget-image\" data-id=\"4bbafdc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"320\" height=\"341\" src=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/107_ISurTec_Neural_Tissue-1.jpg\" class=\"attachment-full size-full wp-image-877\" alt=\"\" srcset=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/107_ISurTec_Neural_Tissue-1.jpg 320w, https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/107_ISurTec_Neural_Tissue-1-282x300.jpg 282w\" sizes=\"auto, (max-width: 320px) 100vw, 320px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2581\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2581\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> <div class=\"icon-block\"><img loading=\"lazy\" decoding=\"async\" src=\"..\/wp-content\/uploads\/2025\/03\/icon-customer-research.svg\" width=\"80\" height=\"80\" \/><\/div><div class=\"text-block\"><h3>Customer Research<\/h3><p>ISurTec works with companies internationally to craft solutions for difficult surface modification and coating challenges.\u00a0From basic idea to a commercial solution with tight specifications, we will collaborate with you to design and implement a solution, then support your technology transfer.<\/p><\/div> <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"45\" height=\"45\" viewBox=\"0 0 45 45\" fill=\"none\"><rect x=\"-1\" y=\"-1\" width=\"43\" height=\"43\" rx=\"21.5\" transform=\"matrix(-4.37114e-08 -1 -1 4.37114e-08 43 43)\" stroke=\"#69C4EB\" stroke-width=\"2\"><\/rect><path d=\"M17 23.9997L22.7003 18.2997L28.401 24\" stroke=\"#69C4EB\" stroke-width=\"1.5\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"45\" height=\"45\" viewBox=\"0 0 45 45\" fill=\"none\"><rect x=\"44\" y=\"1\" width=\"43\" height=\"43\" rx=\"21.5\" transform=\"rotate(90 44 1)\" stroke=\"#F08119\" stroke-width=\"2\"><\/rect><path d=\"M17 21.0003L22.7003 26.7003L28.401 21\" stroke=\"#F08119\" stroke-width=\"1.5\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2581\" class=\"elementor-element elementor-element-f6850a7 e-con-full e-flex e-con e-child\" data-id=\"f6850a7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2581\" class=\"elementor-element elementor-element-fe9e8cf e-flex e-con-boxed e-con e-child\" data-id=\"fe9e8cf\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e487d17 elementor-widget elementor-widget-heading\" data-id=\"e487d17\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">PhotoPrime SR Lab-on-a-Chip<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6f2ad15 elementor-widget elementor-widget-text-editor\" data-id=\"6f2ad15\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tISurTec developed PhotoPrime SR 330 Primer to bond hydrophilic coating to a broad range of medical and biotech devices. This technology has found additional uses as an adhesion layer across a number of interesting applications, including drug eluting catheters and, in this case, lab-on-a-chip technology.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-558ec93 btn-animated1 elementor-widget elementor-widget-button\" data-id=\"558ec93\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/ISurTec-PhotoPrimeSR-Silicon-CaseStudy_finaldraft.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"30\" height=\"30\" viewBox=\"0 0 30 30\" fill=\"none\"><rect width=\"30\" height=\"30\" rx=\"15\" fill=\"#F08119\"><\/rect><path d=\"M14.9149 18.4905L18.715 14.6903M18.715 14.6903L14.9147 10.8898M18.715 14.6903L10.6676 14.6903\" stroke=\"white\" stroke-width=\"1.25\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read Case Study<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fb61026 elementor-widget elementor-widget-heading\" data-id=\"fb61026\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">PhotoPrime SR Silicone Drainage Catheters<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d473b34 elementor-widget elementor-widget-text-editor\" data-id=\"d473b34\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Silicone rubber is increasingly used in medical devices, implantables, and wearables due to its biocompatibility, flexibility, and stability in the body, as well as its lack of leachable chemicals. Silicone rubber is relatively easy to manufacture and form into complex shapes, further lending to its draw as a key medical device material. But when it comes to applying a lubricious coating to silicone rubber, challenges arise.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5c5a158 btn-animated1 elementor-widget elementor-widget-button\" data-id=\"5c5a158\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.zubasti.com\/isurtec\/wp-content\/uploads\/2025\/03\/ISurTec-PhotoPrimeSR-SiliconeRubber-CaseStudy.pdf\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"30\" height=\"30\" viewBox=\"0 0 30 30\" fill=\"none\"><rect width=\"30\" height=\"30\" rx=\"15\" fill=\"#F08119\"><\/rect><path d=\"M14.9149 18.4905L18.715 14.6903M18.715 14.6903L14.9147 10.8898M18.715 14.6903L10.6676 14.6903\" stroke=\"white\" stroke-width=\"1.25\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read Case Study<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-00c7101 elementor-widget elementor-widget-heading\" data-id=\"00c7101\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Flexible Response to Client Needs\u00a0<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-95098a0 elementor-widget elementor-widget-text-editor\" data-id=\"95098a0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tA mid-size medical device manufacturer approached ISurTec about coating a new device with our commercial lubricious coating. However, the company did not yet have prototypes of their devices, which would be produced from polymer sheeting. The client asked us to not only coat the sheeting, but produce prototypes by laser cutting and heat-sealing their CAD designs. While ISurTec does not manufacture medical devices, our engineering lab can assist with prototyping. We successfully delivered two different designs within weeks. The client was then able to use them for physician evaluations in a non-clinical setting. These coated prototypes set the stage for production of the coated device.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ecaacd6 elementor-widget elementor-widget-heading\" data-id=\"ecaacd6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">From feasibility to final product<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c8dbd4a elementor-widget elementor-widget-text-editor\" data-id=\"c8dbd4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tA mid-size international medical device manufacturer came to ISurTec seeking a hydrophilic coating for their balloon catheters, which were composed of several grades of PEBAX, transitioning to nylon with a polyurethane balloon. ISurTec conducted a feasibility study, coating five catheters, including the balloon portion and the distal 10 inches, with our commercial ISurGlide 460 coating over PhotoPrime 955 primer. We tested one of the catheters by staining the coating to demonstrate uniformity and measuring the coefficient of friction of the hydrated coating (COF < 0.02). Satisfied with their internal testing of the coated balloon catheters, the client was ready to move forward with manufacturing, but lacked a coating service or internal coating capabilities in their home country. To assist them, ISurTec provided technology transfer on both the coating equipment and the coating procedure we used on their catheters. The client was then able to build their own equipment and commercially produce the ISurGlide-coated balloon catheters.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2582\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"3\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2582\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><div class=\"e-n-accordion-item-title-text\"> <div class=\"icon-block\"><img loading=\"lazy\" decoding=\"async\" src=\"..\/wp-content\/uploads\/2025\/03\/icon-internal-research.svg\" width=\"80\" height=\"80\" \/><\/div><div class=\"text-block\"><h3>Internal Research<\/h3><p>In addition to performing government and customer research, ISurTec is proud to perform internal research \u2013 which has resulted in impressive technology.\u00a0<\/p><\/div> <\/div><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"45\" height=\"45\" viewBox=\"0 0 45 45\" fill=\"none\"><rect x=\"-1\" y=\"-1\" width=\"43\" height=\"43\" rx=\"21.5\" transform=\"matrix(-4.37114e-08 -1 -1 4.37114e-08 43 43)\" stroke=\"#69C4EB\" stroke-width=\"2\"><\/rect><path d=\"M17 23.9997L22.7003 18.2997L28.401 24\" stroke=\"#69C4EB\" stroke-width=\"1.5\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"45\" height=\"45\" viewBox=\"0 0 45 45\" fill=\"none\"><rect x=\"44\" y=\"1\" width=\"43\" height=\"43\" rx=\"21.5\" transform=\"rotate(90 44 1)\" stroke=\"#F08119\" stroke-width=\"2\"><\/rect><path d=\"M17 21.0003L22.7003 26.7003L28.401 21\" stroke=\"#F08119\" stroke-width=\"1.5\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2582\" class=\"elementor-element elementor-element-184dc71 e-con-full e-flex e-con e-child\" data-id=\"184dc71\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2582\" class=\"elementor-element elementor-element-5276021 e-flex e-con-boxed e-con e-child\" data-id=\"5276021\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-033e565 btn-animated1 elementor-widget elementor-widget-button\" data-id=\"033e565\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.zubasti.com\/isurtec\/isurglide-plus\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"30\" height=\"30\" viewBox=\"0 0 30 30\" fill=\"none\"><rect width=\"30\" height=\"30\" rx=\"15\" fill=\"#F08119\"><\/rect><path d=\"M14.9149 18.4905L18.715 14.6903M18.715 14.6903L14.9147 10.8898M18.715 14.6903L10.6676 14.6903\" stroke=\"white\" stroke-width=\"1.25\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">ISurGlide Plus<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0832402 elementor-widget elementor-widget-text-editor\" data-id=\"0832402\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Innovative hydrophilic primer + topcoat with excellent durability.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f14cc44 btn-animated1 elementor-widget elementor-widget-button\" data-id=\"f14cc44\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.zubasti.com\/isurtec\/isurcell\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"30\" height=\"30\" viewBox=\"0 0 30 30\" fill=\"none\"><rect width=\"30\" height=\"30\" rx=\"15\" fill=\"#F08119\"><\/rect><path d=\"M14.9149 18.4905L18.715 14.6903M18.715 14.6903L14.9147 10.8898M18.715 14.6903L10.6676 14.6903\" stroke=\"white\" stroke-width=\"1.25\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">ISurCell<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3ff0911 elementor-widget elementor-widget-text-editor\" data-id=\"3ff0911\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tUltra low attachment coating \u2013 ideal for organoid creation.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f58106b btn-animated1 elementor-widget elementor-widget-button\" data-id=\"f58106b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.zubasti.com\/isurtec\/isurtherm\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"30\" height=\"30\" viewBox=\"0 0 30 30\" fill=\"none\"><rect width=\"30\" height=\"30\" rx=\"15\" fill=\"#F08119\"><\/rect><path d=\"M14.9149 18.4905L18.715 14.6903M18.715 14.6903L14.9147 10.8898M18.715 14.6903L10.6676 14.6903\" stroke=\"white\" stroke-width=\"1.25\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">ISurTherm<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9474d8f elementor-widget elementor-widget-text-editor\" data-id=\"9474d8f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tThermoresponsive coating \u2013 releases cells at room temperature.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<script type=\"application\/ld+json\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Government Research\\u00a0 ISurTec is strongly committed to research and development, with an interdisciplinary team of scientists and engineers focused on developing new coated products for the scientific and medical communities. Our research is supported by the National Institutes of Health (NIH) through the Small Business Innovative Research Program (SBIR).\\u00a0\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"Coatings for Ureteral Stents - Advancing Ureteral Stent Technology\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tDid you know that 50% of patients with ureteral stents experience complications such as painful encrustation and infections? Over time, ureteral stents and other devices in the urological tract can become encrusted with calcium and magnesium salts. ISurTec\\u2019s innovative anti-encrustation coating has demonstrated the ability to reduce calcium deposition by over 80% after just one month. This significant advancement represents a major improvement in patient well-being. A heartfelt thanks to our dedicated team for its efforts and the NIH SBIR program for funding this groundbreaking research (NIH-R44DK097934).\\u00a0\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\n\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\n\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tUncoated PU Ureteral Stent\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tISurTec-coated PU Ureteral Stent\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tUreteral stents and other devices in the urological tract can encrust with Ca2+ and Mg2+ salts over time. ISurTec\\u2019s anti-encrustation coating reduces Ca2+ deposition > 80% after 1 month.\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\tAddressing Shunt Failure in Hydrocephalus Treatment\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tOver 30% of implantable cerebrospinal fluid (CSF) shunts used to treat hydrocephalus fail within the first year. Shunt failure necessitates surgical reintervention, which, if delayed, can lead to severe consequences, including brain damage or death. Implantable silicone shunts have been used successfully for decades to treat this disorder. While silicone is a well-established and biocompatible material for implantation, the primary, often unaddressed, cause of shunt failure is clogging due to embolism and tissue ingrowth. Through funding provided by the NIH SBIR Program, ISurTec is developing a novel coating designed to reduce shunt failure by minimizing cell and tissue adhesion to the shunt material. By improving the longevity and reliability of CSF shunts, we hope to enhance patient outcomes and reduce the need for repeated surgical interventions (NIH-R44NS119007).\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\n\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\tNeural Tissue Engineering Scaffolds\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tOur scaffolds will be produced in a standardized format compatible with common electrophysiology equipment, such as multielectrode arrays. The scaffolds are designed to enable high-throughput electrophysiological assays with high predictive power for multiple neurotransmitter systems, including glutamatergic, cholinergic, dopaminergic, serotonergic, noradrenergic, and GABAergic circuits.\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\tNanofiber Membrane Inserts for 96-well Plates\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\n\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tISurTec has developed cell culture inserts with a nanofiber membrane for growing cells in a more in vivo-like environment.  The topography of our electrospun membranes mimics the extracellular matrix that cells excrete around themselves as they mature.  Cells can be seeded in suspension in the insert cup or bioprinted on the insert underside.  The nanofiber membranes are electrospun from either permanent materials, such as PET growth surfaces, or materials that biodegrade over time.  Biodegradable membranes allow cells to be grown on both the apical and basolateral sides of the insert membrane eventually forming a mature barrier membrane as the insert membrane degrades.  Please inquire if you are interested in beta testing ISurTec cell culture inserts!\"}},{\"@type\":\"Question\",\"name\":\"Customer ResearchISurTec works with companies internationally to craft solutions for difficult surface modification and coating challenges.\\u00a0From basic idea to a commercial solution with tight specifications, we will collaborate with you to design and implement a solution, then support your technology transfer.\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"PhotoPrime SR Lab-on-a-Chip\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tISurTec developed PhotoPrime SR 330 Primer to bond hydrophilic coating to a broad range of medical and biotech devices. This technology has found additional uses as an adhesion layer across a number of interesting applications, including drug eluting catheters and, in this case, lab-on-a-chip technology.\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tRead Case Study\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\tPhotoPrime SR Silicone Drainage Catheters\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tSilicone rubber is increasingly used in medical devices, implantables, and wearables due to its biocompatibility, flexibility, and stability in the body, as well as its lack of leachable chemicals. Silicone rubber is relatively easy to manufacture and form into complex shapes, further lending to its draw as a key medical device material. But when it comes to applying a lubricious coating to silicone rubber, challenges arise.\\u00a0\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tRead Case Study\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\tFlexible Response to Client Needs\\u00a0\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tA mid-size medical device manufacturer approached ISurTec about coating a new device with our commercial lubricious coating. However, the company did not yet have prototypes of their devices, which would be produced from polymer sheeting. The client asked us to not only coat the sheeting, but produce prototypes by laser cutting and heat-sealing their CAD designs. While ISurTec does not manufacture medical devices, our engineering lab can assist with prototyping. We successfully delivered two different designs within weeks. The client was then able to use them for physician evaluations in a non-clinical setting. These coated prototypes set the stage for production of the coated device.\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\tFrom feasibility to final product\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tA mid-size international medical device manufacturer came to ISurTec seeking a hydrophilic coating for their balloon catheters, which were composed of several grades of PEBAX, transitioning to nylon with a polyurethane balloon. ISurTec conducted a feasibility study, coating five catheters, including the balloon portion and the distal 10 inches, with our commercial ISurGlide 460 coating over PhotoPrime 955 primer. We tested one of the catheters by staining the coating to demonstrate uniformity and measuring the coefficient of friction of the hydrated coating (COF < 0.02). Satisfied with their internal testing of the coated balloon catheters, the client was ready to move forward with manufacturing, but lacked a coating service or internal coating capabilities in their home country. To assist them, ISurTec provided technology transfer on both the coating equipment and the coating procedure we used on their catheters. The client was then able to build their own equipment and commercially produce the ISurGlide-coated balloon catheters.\"}},{\"@type\":\"Question\",\"name\":\"Internal ResearchIn addition to performing government and customer research, ISurTec is proud to perform internal research \\u2013 which has resulted in impressive technology.\\u00a0\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"ISurGlide Plus\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tInnovative hydrophilic primer + topcoat with excellent durability.\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tISurCell\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tUltra low attachment coating \\u2013 ideal for organoid creation.\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tISurTherm\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\n\\t\\t\\t\\t\\t\\t\\t\\t\\tThermoresponsive coating \\u2013 releases cells at room temperature.\"}}]}<\/script>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>RESEARCH Our goal is to provide you with the ideal coating for your application as efficiently as possible, using a streamlined, straightforward process. Government Research\u00a0 ISurTec is strongly committed to research and development, with an interdisciplinary team of scientists and engineers focused on developing new coated products for the scientific and medical communities. Our research [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-75","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.zubasti.com\/isurtec\/wp-json\/wp\/v2\/pages\/75","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.zubasti.com\/isurtec\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.zubasti.com\/isurtec\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.zubasti.com\/isurtec\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zubasti.com\/isurtec\/wp-json\/wp\/v2\/comments?post=75"}],"version-history":[{"count":5,"href":"https:\/\/www.zubasti.com\/isurtec\/wp-json\/wp\/v2\/pages\/75\/revisions"}],"predecessor-version":[{"id":2341,"href":"https:\/\/www.zubasti.com\/isurtec\/wp-json\/wp\/v2\/pages\/75\/revisions\/2341"}],"wp:attachment":[{"href":"https:\/\/www.zubasti.com\/isurtec\/wp-json\/wp\/v2\/media?parent=75"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}